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Dolutegravir sodium

Drug ingredient

CAS 1051375-19-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1051375-19-9
1 Na⁺
US productionNot reported
Import value, 2024$6.4B
Top sourceSingapore 36%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293499 · basket

These shares come from HS customs code 293499, which covers 575 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
SG 36%SingaporeIE 23%IrelandCN 11%ChinaCH 6%SwitzerlandIN 5%India
14 FDA-registered drug labelers
Aurobindo Pharma Limited
Chromo Laboratories India Private Limited
Glaxo Operations UK Ltd
Glaxo Wellcome Manufacturing Pte. Ltd
GlaxoSmithKline LLC
HETERO LABS LIMITED
Honour Lab Limited
Matrix Pharmacorp Private Limited
MSN Life Sciences Private Limited
Shanghai Desano Chemical Pharmaceutical Co., Ltd.
Shionogi Pharma Co., Ltd.
ST. MARY'S MEDICAL PARK PHARMACY
ViiV Healthcare Company
Viyash Life Sciences Private Limited

Why It Matters

Sectors
Health
Downstream Uses

Appears in 5 drug and cosmetic product listings (FDA).

  • •Juluca
  • •Tivicay PD
  • •Tivicay
  • •Triumeq
  • •Dovato
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS1051375-19-9
PubChem CID46216142
DTXSIDDTXSID201027849
FormulaC20H18F2N3NaO5
Mol. Weight441.4 g/mol
SMILESCC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]

Data Sources

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Brief citations

Dolutegravir sodium (CAS 1051375-19-9) https://chemicalindependence.com/chemical/1051375-19-9/ PubChem: 46216142. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/46216142 FDA National Drug Code directory: CAS 1051375-19-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293499 for CAS 1051375-19-9. Reporting year: 2024. https://usatrade.census.gov/