N-Methyldiethanolamine

CAS 105-59-9

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$26M

Top sourceIndia 51%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023.

Where It Comes From

Customs basis: HS 292217 · exact

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 51%IndiaBE 47%BelgiumDE 1%Germany

Canada
United Arab Emirates

EPA-registered manufacturers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Basf

Dow Chemical

Huntsman

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Eastman Chemical

EPA-registered importers (4)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Basf Se · DE Germany

Chs

Ineos Gas Spec Technology Group

United Refining

Why It Matters

Sectors

EnergyCore Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 4 sectors as 5 functional roles.

•Intermediate in All Other Basic Organic Chemical ManufacturingProcessing as a reactant
•Processing aids, specific to petroleum production in Petroleum Refineries (100%)Processing as a reactant
•pH regulating agent in All Other Basic Organic Chemical Manufacturing (10%)Processing—incorporation into formulation, mixture, or reaction product
•Solvent in Oil and Gas Drilling, Extraction, and Support activities (30%)Processing—repackaging
•Processing aids, specific to petroleum production in All Other Chemical Product and Preparation Manufacturing (100%)Processing as a reactant
•Absorbent in Petroleum Refineries (100%)Processing as a reactant

Chemical Identity

CAS105-59-9

PubChem CID7767

DTXSIDDTXSID8025591

FormulaC5H13NO2

Mol. Weight119.16 g/mol

SMILESCN(CCO)CCO

Data Sources

EPA CompTox (DSSTox) · DTXSID8025591Retrieved 2026-04-06
PubChem · compound 7767Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

N-Methyldiethanolamine (CAS 105-59-9) https://chemicalindependence.com/chemical/105-59-9/ EPA CompTox (DSSTox): DTXSID8025591. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID8025591 PubChem: 7767. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/7767 EPA Chemical Data Reporting: 105-59-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 105-59-9. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292217 for CAS 105-59-9. Reporting year: 2024. https://usatrade.census.gov/