4-Nitrosophenol

CAS 104-91-6

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$11M

Import volumeZero

Top sourceIndia 78%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 290899 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 290899, which covers 60 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

IN 78%IndiaCN 19%ChinaJP 1%JapanAE 1%United Arab Emirates

Italy
Hungary
Germany
Netherlands
Canada
Mexico

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Archroma U.S

Why It Matters

Sectors

Core Chemicals

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in All Other Basic Organic Chemical Manufacturing (100%)Processing as a reactant

Vendor Pricing

$3.24/gA2B Chem LLC

CountryUnited States

Pack$81.00 / 25 g

Purity98%

Vendors4 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

3 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$3.44	25 g	98%
Combi-Blocks, Inc.	United States	$7.20	25 g	98%
Otava, Ltd.	Ukraine	$2280.00	50 mg	95%

Chemical Identity

CAS104-91-6

PubChem CID7729

DTXSIDDTXSID0025991

FormulaC6H5NO2

Mol. Weight123.11 g/mol

SMILESC1=CC(=CC=C1N=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID0025991Retrieved 2026-04-06
PubChem · compound 7729Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

4-Nitrosophenol (CAS 104-91-6) https://chemicalindependence.com/chemical/104-91-6/ EPA CompTox (DSSTox): DTXSID0025991. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0025991 PubChem: 7729. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/7729 EPA Chemical Data Reporting: 104-91-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 104-91-6. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 290899 for CAS 104-91-6. Reporting year: 2024. https://usatrade.census.gov/