Benzonatate

Drug ingredient

CAS 104-31-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 104-31-4
US productionNot reported
Import value, 2024$218M
Top sourceGermany 21%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 340242 · basket

These shares come from HS customs code 340242, which covers 45 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
DE 21%GermanyKR 11%South KoreaIT 10%ItalyCA 9%CanadaMX 8%Mexico
44 FDA-registered drug labelers
A-S Medication Solutions
American Health Packaging
Amneal Pharmaceuticals LLC
Aphena Pharma Solutions - Tennessee, LLC
Ascend Laboratories, LLC
Asclemed USA, Inc.
AvKARE
Bionpharma Inc.
Bryant Ranch Prepack
Camber Pharmaceuticals, Inc.
Cardinal Health 107, LLC
Catalent Pharma Solutions, LLC
Chartwell RX, LLC
Coupler LLC
DIRECT RX
Epic Pharma LLC
Formosa Laboratories, Inc.
Golden State Medical Supply, Inc.
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Major Pharmaceuticals
NCS HealthCare of KY, LLC dba Vangard Labs
Northwind Health Company, LLC
NuCare Pharmaceuticals,Inc.
NURAY CHEMICALS PRIVATE LIMITED
Patheon Softgels Inc.
PD-Rx Pharmaceuticals, Inc.
Precision Dose, Inc.
Preferred Pharmaceuticals Inc
Proficient Rx LP
QPharma Inc
Redpharm Drug
RedPharm Drug, Inc.
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Siegfried (Nantong) Pharmaceuticals Co, Ltd
Siegfried Evionnaz SA
Sportpharm, Inc. dba Sportpharm
ST. MARY'S MEDICAL PARK PHARMACY
Strides Pharma Science Limited
TAGI Pharma, Inc.
W. R. GRACE & CO.-CONN.
XLCare Pharmaceuticals, Inc.
Zydus Lifesciences Limited
Zydus Pharmaceuticals USA Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Benzonatate
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$290.00/gCombi-Blocks, Inc.
CountryUnited States
Pack$290.00 / 1 g
Purity95%
Vendors12 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS104-31-4
PubChem CID7699
DTXSIDDTXSID9022655
FormulaC30H53NO11
Mol. Weight603.7 g/mol
SMILESCCCCNC1=CC=C(C=C1)C(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOC

Data Sources

Brief citations

Benzonatate (CAS 104-31-4) https://chemicalindependence.com/chemical/104-31-4/ PubChem: 7699. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/7699 FDA National Drug Code directory: CAS 104-31-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 340242 for CAS 104-31-4. Reporting year: 2024. https://usatrade.census.gov/