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Daptomycin

Drug ingredient

CAS 103060-53-3

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 103060-53-3
US productionNot reported
Import value, 2024$546M
Top sourceItaly 41%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 294190 · basket

These shares come from HS customs code 294190, which covers 90 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IT 41%ItalyCN 24%ChinaDK 9%DenmarkHR 6%CroatiaIN 6%India
34 FDA-registered drug labelers
Accord Healthcare Inc.
ACS Dobfar S.p.A.
APOTEX CORP.
Baxter Healthcare Corporation
BE Pharmaceuticals Inc.
Biocon Pharma Inc.
BluePoint Laboratories
Camber Pharmaceuticals, Inc.
Chongqing Daxin Pharmaceutical Co. Ltd.
Civica, Inc.
Dr. Reddy's Laboratories Inc.,
Eugia US LLC
Fresenius Kabi USA, LLC
Hainan Poly Pharm., Co., Ltd.
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Hikma Pharmaceuticals USA Inc.
Hisun Pharmaceutical (Hangzhou) Co., Ltd.
Hisun Pharmaceuticals USA, Inc.
Hospira, Inc.
Livzon Group Fuzhou Fuxing Pharmaceutical Co., Ltd.
MAIA Pharmaceuticals, Inc.
Meitheal Pharmaceuticals Inc.
Mylan Institutional LLC
NorthStar RxLLC
Olon SpA
Par Health USA, LLC
Patheon Italia S.p.A
Qilu Pharmaceutical Co., Ltd.
Sagent Pharmaceuticals
Sintetica US LLC
Slate Run Pharmaceuticals, LLC
Xellia Pharmaceuticals USA LLC
Zhejiang Changhai Pharmaceuticals Co., Ltd.
Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Daptomycin
  • •Daptomycin in Sodium Chloride
  • •Dapzura RT
FDA Shortage Status
No FDA shortage records

Chemical Identity

CAS103060-53-3
PubChem CID21585658
DTXSIDDTXSID1041009
FormulaC72H101N17O26
Mol. Weight1620.7 g/mol
SMILESCCCCCCCCCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC3C(OC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC3=O)CCCN)CC(=O)O)C)CC(=O)O)CO)C(C)CC(=O)O)CC(=O)C4=CC=CC=C4N)C

Data Sources

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Brief citations

Daptomycin (CAS 103060-53-3) https://chemicalindependence.com/chemical/103060-53-3/ PubChem: 21585658. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/21585658 FDA National Drug Code directory: CAS 103060-53-3. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 294190 for CAS 103060-53-3. Reporting year: 2024. https://usatrade.census.gov/