2,5-Bis(p-toluidino)terephthalic acid

CAS 10291-28-8

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$503M

Top sourceChina 25%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292249 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 292249, which covers 170 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 25%ChinaIN 17%IndiaSG 13%SingaporeIT 9%ItalyCH 7%Switzerland

Argentina
Poland
Portugal
Lithuania
Ukraine
Finland
Spain
Egypt
Sweden
Austria
Israel
Latvia
Belgium
Ireland
Mexico
Australia
Peru
Czech Republic
Colombia
Hong Kong

Why It Matters

Sectors

Textiles

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Pigment in Synthetic Dye and Pigment Manufacturing (100%)Processing as a reactant

Chemical Identity

CAS10291-28-8

PubChem CID82524

DTXSIDDTXSID4065024

FormulaC22H20N2O4

Mol. Weight376.4 g/mol

SMILESCC1=CC=C(C=C1)NC2=CC(=C(C=C2C(=O)O)NC3=CC=C(C=C3)C)C(=O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID4065024Retrieved 2026-04-06
PubChem · compound 82524Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2,5-Bis(p-toluidino)terephthalic acid (CAS 10291-28-8) https://chemicalindependence.com/chemical/10291-28-8/ EPA CompTox (DSSTox): DTXSID4065024. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID4065024 PubChem: 82524. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/82524 EPA Chemical Data Reporting: 10291-28-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 10291-28-8. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292249 for CAS 10291-28-8. Reporting year: 2024. https://usatrade.census.gov/