2-Methoxyethyl cyanoacetate

CAS 10258-54-5

Companies reported imports and no US production of this chemical to EPA for 2023.

US productionZero

Import value, 2024$281M

Import volume8.8K lb

Import dependency100%

Top sourceChina 31%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

2-Methoxyethyl cyanoacetate · US import value by year

2013: $339M · Peak 2022: $410M · 2024: $281M · 2025: $254M

Where It Comes From

Customs basis: HS 292690 · basket

EPA reports by year

2023: US production Zero · Imports 8.8K lb
2019: US production Zero · Imports 48.3K lb

These shares come from HS customs code 292690, which covers 191 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 31%ChinaIT 15%ItalyGB 14%United KingdomIN 11%IndiaJP 8%Japan

South Korea
Spain
Ireland
Ukraine
Malaysia
Brazil
Hong Kong
Latvia
Australia

EPA-registered importers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Henkel

Why It Matters

Sectors

ElectronicsMetals & Mining

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

Used in 3 sectors as 1 functional role.

•Monomers in Electrical Equipment, Appliance, and Component Manufacturing (20%)Processing as a reactant
•Monomers in Machinery Manufacturing (40%)Processing as a reactant
•Monomers in Computer and Electronic Product Manufacturing (41%)Processing as a reactant

Vendor Pricing

$0.72/gCombi-Blocks, Inc.

CountryUnited States

Pack$360.00 / 500 g

Purity98%

Vendors14 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

13 more vendors

Vendor	Country	$/g	Pack	Purity
Aaron Chemicals LLC	Hong Kong	$0.75	500 g	95%
Angene Chemical	China → Hong Kong	$0.75	500 g	95%
BLD Pharmatech Ltd.	China	$0.81	500 g	95%
A2B Chem LLC	United States	$1.00	25 g	98%
AA BLOCKS	United States	$1.08	500 g	95%
AstaTech (2 weeks)	United States	$1.19	100 g	95%
Ambeed, Inc.	United States	$1.36	100 g	95%
BLD Pharmatech Co., Limited	United States	$1.40	25 g	95%
AK Scientific, Inc.	United States	$7.84	25 g	98%
Angene International Limited	United States	$13.44	25 g	98%
Interbioscreen	Hong Kong	$24.00	10 g	95%
Acrotein ChemBio, Inc.	United States	$33.00	25 g	—
Angene	China → Hong Kong	$4266.67	30 mg	95%

Chemical Identity

CAS10258-54-5

PubChem CID25106

DTXSIDDTXSID0038831

FormulaC6H9NO3

Mol. Weight143.14 g/mol

SMILESCOCCOC(=O)CC#N

Data Sources

EPA CompTox (DSSTox) · DTXSID0038831Retrieved 2026-04-06
PubChem · compound 25106Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

2-Methoxyethyl cyanoacetate (CAS 10258-54-5) https://chemicalindependence.com/chemical/10258-54-5/ EPA CompTox (DSSTox): DTXSID0038831. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID0038831 PubChem: 25106. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/25106 EPA Chemical Data Reporting: 10258-54-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 10258-54-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292690 for CAS 10258-54-5. Reporting year: 2024. https://usatrade.census.gov/