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glyburide

Drug ingredient

CAS 10238-21-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 10238-21-8
US productionNot reported
Import value, 2024$2.0B
Top sourceIreland 63%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293590 · basket

These shares come from HS customs code 293590, which covers 182 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
IE 63%IrelandSG 14%SingaporeIN 7%IndiaCN 7%ChinaCH 2%Switzerland
23 FDA-registered drug labelers
A-S Medication Solutions
Aurobindo Pharma Limited
Bryant Ranch Prepack
Cadila Pharmaceuticals Limited
Cambrex Profarmaco Milano Srl
Chartwell RX, LLC
Coupler LLC
Dipharma Francis Srl
Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.
Modavar Pharmaceuticals LLC
Nivagen Pharmaceuticals, Inc.
Northwind Health Company, LLC
NuCare Pharmaceuticals, Inc.
OPELLA HEALTHCARE INTERNATIONAL SAS
Preferred Pharmaceuticals Inc.
Proficient Rx LP
REMEDYREPACK INC.
Rising Pharma Holdings, Inc.
Sri Krishna Pharmaceuticals Ltd. Unit I
TEVA Pharmaceuticals USA Inc
USV Private Limited
Zydus Lifesciences Limited
Zydus Pharmaceuticals (USA) Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 3 drug and cosmetic product listings (FDA).

  • •Glyburide
  • •glyburide-metformin hydrochloride
  • •Glyburide and Metformin Hydrochloride
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Glyburide Tablet

    Shortage listed since June 10, 2025

See all current drug shortages

Vendor Pricing

$0.27/gBLD Pharmatech GmbH
CountryGermany
Pack$137.00 / 500 g
Purity98%
Vendors32 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

31 more vendors
VendorCountry$/gPackPurity
BLD Pharmatech Ltd.China$0.27500 g98%
A2B Chem LLCUnited States$0.30500 g98%
Combi-Blocks, Inc.United States$0.30500 g98%
Aaron Chemicals LLCHong Kong$0.31100 g98%
AA BLOCKSUnited States$0.35500 g98%
Angene ChemicalChina → Hong Kong$0.38100 g98%
BLD Pharmatech Co., LimitedUnited States$0.40100 g98%
Ambeed, Inc.United States$0.40100 g98%
AK Scientific SpecializedUnited States$0.86100 g95%
AstaTech, IncUnited States$1.00100 g95%
AK Scientific, Inc.United States$1.24100 g98%
Angene International LimitedUnited States$2.26100 g98%
Fulfilled by MolportLatvia$5.001 g98%
Apexbio Technology LLCUnited States$14.005 g99.76%
MedKoo Biosciences, IncUnited States$22.0025 g98%
MedChemExpress MCESweden$22.995 g99.94%
Sigma-Aldrich (Rush Stock)Germany$30.6210 g—
Sigma-AldrichGermany$30.6210 g—
MolnovaChina$48.001 g99%
TargetMol ChemicalsChina → United States$53.001 g99.77%
InterbioscreenHong Kong$129.0010 g95%
Labotest KGGermany$217.805000 mg90%
CliniSciences GmbHSwitzerland$322.50100 mg99%
ChemFacesChina$1500.0020 mg98%
Maybridge, Ltd.United Kingdom$2414.30100 mg90%
Otava, Ltd. (2 weeks)Ukraine$2724.0050 mg90%
Princeton BioMolecular Research (SC)United States$2900.00100 mg90%
Vitas M Chemical LimitedHong Kong$3170.00100 mg90%
ChemDiv, Inc.United States$4070.00100 mg90%
AngeneChina → Hong Kong$4266.6730 mg98%
TimTec, LLCUnited States$9333.3330 mg90%

Chemical Identity

CAS10238-21-8
PubChem CID3488
DTXSIDDTXSID0037237
FormulaC23H28ClN3O5S
Mol. Weight494 g/mol
SMILESCOC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

Data Sources

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Brief citations

glyburide (CAS 10238-21-8) https://chemicalindependence.com/chemical/10238-21-8/ PubChem: 3488. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/3488 FDA National Drug Code directory: CAS 10238-21-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 10238-21-8. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293590 for CAS 10238-21-8. Reporting year: 2024. https://usatrade.census.gov/