Minocycline

Drug ingredient

CAS 10118-90-8

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

US productionNot reported

Import value, 2024$62M

Top sourceChina 82%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 294130 · basket

These shares come from HS customs code 294130, which covers 10 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 82%ChinaCH 5%SwitzerlandBG 4%BulgariaTH 4%ThailandIT 2%Italy

Canada
United Kingdom
Israel
India
South Korea

1 FDA-registered drug labeler

Zhejiang Hisun Pharmaceutical Co., Ltd.

Why It Matters

Sectors

Health

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No Shortage

Shortage History

Rows group FDA shortage filings by drug product. Each manufacturer makes its own FDA shortage filing, so one product can carry several reports at once: Available, Limited Availability, Unavailable or to be discontinued.

to be discontinued
Minocycline Hydrochloride Capsule
Shortage listed since May 23, 2025

See all current drug shortages

Chemical Identity

CAS10118-90-8

PubChem CID54675783

DTXSIDDTXSID1045033

FormulaC23H27N3O7

Mol. Weight457.5 g/mol

SMILESCN(C)C1C2CC3CC4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C

Data Sources

PubChem · compound 54675783Retrieved 2026-04-07
FDA National Drug Code directoryRetrieved 2026-04-25
FDA Drug ShortagesRetrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Minocycline (CAS 10118-90-8) https://chemicalindependence.com/chemical/10118-90-8/ PubChem: 54675783. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/54675783 FDA National Drug Code directory: CAS 10118-90-8. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 10118-90-8. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 294130 for CAS 10118-90-8. Reporting year: 2024. https://usatrade.census.gov/