Iron(III) pyrophosphate

Drug ingredient

CAS 10058-44-3

EPA’s 2019 records show zero U.S. production for this drug ingredient.

Molecular structure of 10058-44-3 — 4 Fe³⁺

US productionZero

Import value, 2024$95M

Top sourceCanada 30%

EPA lists this chemical for 2019 but publishes zero or no volume for both production and imports.

Why supply is unknown

Production is reported production, not a complete census of factories. Production reporting year: 2019. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 283539 · basket

EPA reports by year

2019: US production Zero · Imports Zero

These shares come from HS customs code 283539, which covers 21 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CA 30%CanadaDE 19%GermanyMY 17%MalaysiaCN 13%ChinaIT 9%Italy

Spain
Belgium
Japan
Poland
Taiwan
Switzerland
South Korea
Singapore
Netherlands
Denmark
United Kingdom
Slovakia

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Icl Specialty Products North America

Why It Matters

Sectors

Health

Downstream Uses

Appears in 20 drug and cosmetic product listings (FDA).

•Bestmade Natural Products BM18
•Bestmade Natural Products Bio9
•Bestmade Natural Products Bio10
•Bestmade Natural Products Bio11
•Bestmade Natural Products BM34
•Bestmade Natural Products Bio3
•Bestamade Natural Products Bio15
•Bestmade Natural Products BM28

Show all 20

•Bestmade Natural Products Bio12
•Bestmade Natural Products Bio16
•Bestmade Natural Products Bio17
•Bestmade Natural Products Bio6
•Bestmade Natural Products Bio24
•Bestmade Natural Products Bio5
•Bestmade Natural Products Bio1
•Bestmade Natural Products Bio19
•Bestmade Natural Products Bio7
•Bestmade Natural Products Bio8
•Bestmade Natural Products Bio23
•Bestmade Natural Products Ferr Phos

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Chemical Identity

CAS10058-44-3

PubChem CID24877

DTXSIDDTXSID6047600

FormulaFe4O21P6

Mol. Weight745.21 g/mol

SMILES[O-]P(=O)([O-])OP(=O)([O-])[O-].[O-]P(=O)([O-])OP(=O)([O-])[O-].[O-]P(=O)([O-])OP(=O)([O-])[O-].[Fe+3].[Fe+3].[Fe+3].[Fe+3]

Data Sources

EPA CompTox (DSSTox) · DTXSID6047600Retrieved 2026-04-06
PubChem · compound 24877Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2019 · Retrieved 2026-10-04
FDA National Drug Code directoryRetrieved 2026-04-07
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

Iron(III) pyrophosphate (CAS 10058-44-3) https://chemicalindependence.com/chemical/10058-44-3/ EPA CompTox (DSSTox): DTXSID6047600. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID6047600 PubChem: 24877. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/24877 EPA Chemical Data Reporting: 10058-44-3. Reporting year: 2019. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 283539 for CAS 10058-44-3. Reporting year: 2024. https://usatrade.census.gov/