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Monosodium phosphate monohydrate

Drug ingredient

CAS 10049-21-5

sodium phosphate, monobasic, monohydrate

Companies reported imports and no US production of this drug ingredient to EPA for 2023.

Molecular structure of 10049-21-5
1 H₂O · 1 Na⁺
US productionZero
Import value, 2024$26M
Import volume41.9K lb
Import dependency100%
Top sourceGermany 34%

Production is reported production, not a complete census of factories. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Monosodium phosphate monohydrate · US import value by year
$16M2013$37M2022$26M2024$22M2025

2013: $16M · Peak 2022: $37M · 2024: $26M · 2025: $22M

Where It Comes From

Customs basis: HS 283522 · narrow

EPA reports by year
2023
US production Zero · Imports 41.9K lb

These shares come from HS customs code 283522, which covers 6 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
DE 34%GermanyCN 27%ChinaMX 13%MexicoIT 10%ItalyCA 4%Canada
Domestic parents -- activity not disclosed (1)
Acs Chemical
EPA-registered importers (1)
Global Chemical Resources
25 FDA-registered drug labelers
Allegis Pharmaceuticals, LLC
American Regent, Inc.
Amivas, Inc
Avantor Performance Materials, LLC
Beach Products, Inc.
Caplin Steriles Limited
Citra Labs, LLC
Civica, Inc.
Dalton Chemical Laboratories Inc.
DORAL PHARMAMEDICS INC dba A.G. Marin Pharmaceuticals
Fenwal, Inc.
Fresenius Kabi USA, LLC
GLENMARK PHARMACEUTICALS INC., USA
Global Calcium Private Limited
Global Life Sciences Solutions USA LLC
Hospira, Inc.
Hunan Jiudian Pharmaceutical Co.,Ltd.
ICU Medical Inc.
Jost Chemical Co.
Lupin Pharmaceuticals,Inc.
Method Pharmaceuticals
Rising Pharma Holdings, Inc.
Terumo BCT, Ltd
Terumo Corporation
Viatris Specialty LLC

Why It Matters

Sectors
HealthCore Chemicals
Downstream Uses

Appears in 21 drug and cosmetic product listings (FDA).

  • •CPDA-1
  • •Phospha 250 Neutral
  • •Sodium Phosphates
  • •Solucion InterSol
  • •Additive Formula 3
  • •InterSol
  • •Urimar-T CAPS
  • •Teruflex Blood with Diversion Blood Sampling Arm 70 mL CPDA-1
Show all 21
  • •Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate
  • •Uretron D/S
  • •teruflex blood bag system with diversion blood sampling arm 70 ml cpda-1
  • •Pall Sterile Cord Blood Collection Unit
  • •Anticoagulant Citrate Phosphate Dextrose (CPD) Blood-Pack Units in PL 146 Plastic
  • •Me NaPhos MB Hyo 1
  • •Ionosol MB and Dextrose
  • •Rejuvesol
  • •Monobasic Sodium Phosphate and Dibasic Sodium Phosphate
  • •Teruflex Blood Anticoagulant Citrate Phosphate Dextrose Adenine (CPDA-1) for Collection of 450mL of Blood
  • •K Phos Neutral
  • •MB CAPS
  • •Urelle
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$0.01/gAaron Chemicals LLC
CountryHong Kong
Pack$7.00 / 1 kg
Purity98%
Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

15 more vendors
VendorCountry$/gPackPurity
Angene ChemicalChina → Hong Kong$0.01500 g98%
BLD Pharmatech Co., LimitedUnited States$0.021 kg99%
Ambeed, Inc.United States$0.021 kg99%
BLD Pharmatech GmbHGermany$0.031 kg99%
A2B Chem LLCUnited States$0.0350 kg95%
AA BLOCKSUnited States$0.0350 kg99%
BLD Pharmatech Ltd.China$0.041 kg98%
AK Scientific, Inc.United States$0.061 kg98%
Sigma-Aldrich (Rush Stock)Germany$0.091 kg98%
Sigma-AldrichGermany$0.091 kg98%
Fluorochem EUGermany$0.101 kg99%
Fluorochem UKUnited Kingdom$0.101 kg99%
Combi-Blocks, Inc.United States$0.251 kg98%
Angene International LimitedUnited States$0.65250 g—
AngeneChina → Hong Kong$4266.6730 mg98%

Chemical Identity

CAS10049-21-5
PubChem CID516949
DTXSIDDTXSID6073994
FormulaH4NaO5P
Mol. Weight137.99 g/mol
SMILESO.OP(=O)(O)[O-].[Na+]

Data Sources

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Brief citations

Monosodium phosphate monohydrate (CAS 10049-21-5) https://chemicalindependence.com/chemical/10049-21-5/ PubChem: 516949. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/516949 EPA Chemical Data Reporting: 10049-21-5. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 283522 for CAS 10049-21-5. Reporting year: 2024. https://usatrade.census.gov/