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Cobicistat

Drug ingredient

CAS 1004316-88-4

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1004316-88-4
US productionNot reported
Import value, 2024$447M
Top sourceChina 31%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293410 · basket

These shares come from HS customs code 293410, which covers 83 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 31%ChinaDE 25%GermanyMX 19%MexicoJP 13%JapanIN 5%India
11 FDA-registered drug labelers
A-S Medication Solutions
E.R. Squibb & Sons, L.L.C.
Esteve Quimica, SA
Gilead Sciences, Inc.
Honour Lab Limited
Janssen Ortho LLC
Janssen Products LP
Matrix Pharmacorp Private Limited
MSN Life Sciences Private Limited
Patheon Inc.
Yuhan Chemical

Why It Matters

Sectors
Health
Downstream Uses

Appears in 7 drug and cosmetic product listings (FDA).

  • •Prezcobix
  • •Genvoya
  • •Prezcobix PED
  • •Stribild
  • •Tybost
  • •Symtuza
  • •Evotaz
FDA Shortage Status
No Shortage
Shortage History
  • to be discontinued

    Cobicistat Tablet

    Shortage listed since October 7, 2025

  • to be discontinued

    Atazanavir Sulfate; Cobicistat Tablet

    Shortage listed since November 3, 2025

See all current drug shortages

Vendor Pricing

$1480.00/gCombi-Blocks, Inc.
CountryUnited States
Pack$1480.00 / 1 g
Purity97%
Vendors16 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

15 more vendors
VendorCountry$/gPackPurity
MedKoo Biosciences, IncUnited States$3250.001 g98%
Angene ChemicalChina → Hong Kong$4014.001 g98%
A2B Chem LLCUnited States$4090.00100 mg98%
BLD Pharmatech Ltd.China$4384.00250 mg98%
Aaron Chemicals LLCHong Kong$4388.00250 mg98%
AA BLOCKSUnited States$4450.00100 mg98%
MolnovaChina$4780.00100 mg99%
AstaTech, IncUnited States$4970.00100 mg95%
TargetMol ChemicalsChina → United States$5310.00100 mg99.62%
Apexbio Technology LLCUnited States$6050.00200 mg99.94%
MedChemExpress MCESweden$8941.90100 mg99.77%
Angene International LimitedUnited States$11820.00100 mg98%
BLD Pharmatech Co., LimitedUnited States$12100.0010 mg98%
BLD Pharmatech GmbHGermany$12100.0010 mg98%
Cayman EuropeEstonia$36176.0025 mg98%

Chemical Identity

CAS1004316-88-4
PubChem CID25151504
DTXSIDDTXSID00143269
FormulaC40H53N7O5S2
Mol. Weight776 g/mol
SMILESCC(C)C1=NC(=CS1)CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5

Data Sources

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Brief citations

Cobicistat (CAS 1004316-88-4) https://chemicalindependence.com/chemical/1004316-88-4/ PubChem: 25151504. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/25151504 FDA National Drug Code directory: CAS 1004316-88-4. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA Drug Shortages: CAS 1004316-88-4. Retrieved 2026-10-04. https://www.accessdata.fda.gov/scripts/drugshortages/ US Census international trade: HS 293410 for CAS 1004316-88-4. Reporting year: 2024. https://usatrade.census.gov/