alpha-Cyclodextrin

CAS 10016-20-3

U.S. production volumes are classified as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$189M

Top sourceChina 25%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 294000 · basket

EPA reports by year

2023: US production Confidential · Imports Confidential
2019: US production Confidential · Imports Confidential

These shares come from HS customs code 294000, which covers 41 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 25%ChinaDE 16%GermanyIT 11%ItalyCA 7%CanadaDK 7%Denmark

United Kingdom
Belgium
Singapore
Portugal
Finland
South Africa
Hong Kong
New Zealand
Taiwan
Spain
Morocco
Russia
United Arab Emirates
Ukraine
Poland
Australia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Aceto Us

Domestic parents -- activity not disclosed (1)

EPA records name a US company for this chemical but do not disclose whether the company made it here or imported it.

Wacker Chemical

Why It Matters

Sectors

Agriculture

Downstream UsesNot recorded

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Preservative in Agriculture, Forestry, Fishing and Hunting (100%)Processing—incorporation into formulation, mixture, or reaction product

Chemical Identity

CAS10016-20-3

PubChem CID444913

DTXSIDDTXSID7030698

FormulaC36H60O30

Mol. Weight972.8 g/mol

SMILESC(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(O2)C(C7O)O)CO)CO)CO)CO)CO)O)O)O

Data Sources

EPA CompTox (DSSTox) · DTXSID7030698Retrieved 2026-04-06
PubChem · compound 444913Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

← Back to Dashboard ← Back to Agriculture

Brief citations

alpha-Cyclodextrin (CAS 10016-20-3) https://chemicalindependence.com/chemical/10016-20-3/ EPA CompTox (DSSTox): DTXSID7030698. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID7030698 PubChem: 444913. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/444913 EPA Chemical Data Reporting: 10016-20-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 10016-20-3. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 294000 for CAS 10016-20-3. Reporting year: 2024. https://usatrade.census.gov/