Vadadustat

Drug ingredient

CAS 1000025-07-9

This chemical is an active pharmaceutical ingredient used in FDA-regulated drugs.

Molecular structure of 1000025-07-9
US productionNot reported
Import value, 2024$1.3B
Top sourceChina 32%

This chemical is not on EPA’s Toxic Substances Control Act inventory, the list behind EPA’s production survey.

Why supply is unknown

Production is reported production, not a complete census of factories. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 293339 · basket

These shares come from HS customs code 293339, which covers 397 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries
CN 32%ChinaIN 15%IndiaDE 10%GermanyBE 9%BelgiumCH 8%Switzerland
1 FDA-registered drug labeler
Akebia Therapeutics, Inc.

Why It Matters

Sectors
Health
Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

  • •Vafseo
FDA Shortage Status
No FDA shortage records

Vendor Pricing

$2400.00/gCombi-Blocks (back-ordered)
CountryUnited States
Pack$2400.00 / 1 g
Purity97%
Vendors11 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

Chemical Identity

CAS1000025-07-9
PubChem CID23634441
DTXSIDDTXSID501179936
FormulaC14H11ClN2O4
Mol. Weight306.7 g/mol
SMILESC1=CC(=CC(=C1)Cl)C2=CC(=C(N=C2)C(=O)NCC(=O)O)O

Data Sources

Brief citations

Vadadustat (CAS 1000025-07-9) https://chemicalindependence.com/chemical/1000025-07-9/ PubChem: 23634441. Retrieved 2026-04-07. https://pubchem.ncbi.nlm.nih.gov/compound/23634441 FDA National Drug Code directory: CAS 1000025-07-9. Retrieved 2026-04-25. https://open.fda.gov/data/ndc/ FDA National Drug Code directory: bulk match. Retrieved 2026-04-07. https://open.fda.gov/data/ndc/ US Census international trade: HS 293339 for CAS 1000025-07-9. Reporting year: 2024. https://usatrade.census.gov/