1-(Hydroxymethyl)urea

Drug ingredient

CAS 1000-82-4

This drug ingredient has classified U.S. production volumes. EPA withholds the number as confidential business information.

US productionCBI

Confidential Business Information. The EPA withholds this volume because publishing it could reveal the reporting company's trade secrets.

Import value, 2024$371M

Import volumeZero

Top sourceChina 27%

At least one company claimed its 2023 production or import volume for this chemical as confidential, so EPA withholds it.

Why supply is unknown

Production is reported production, not a complete census of factories. US production volume is confidential. Production reporting year: 2023. Import value and source-country shares describe a shared customs category, not a separate chemical measurement.

Where It Comes From

Customs basis: HS 292419 · basket

EPA reports by year

2023: US production Confidential · Imports Zero
2019: US production Confidential · Imports Zero

These shares come from HS customs code 292419, which covers 211 tracked chemicals in total. They estimate the category's origin mix, not this chemical specifically.

Source Countries

Country of origin for US imports, from Census customs data (2024).

CN 27%ChinaIN 18%IndiaDE 14%GermanyIT 10%ItalyGB 6%United Kingdom

Hungary
Austria
Spain
Egypt
Canada
Sweden
Ukraine
Denmark
Israel
Lithuania
Greece
Ireland
Taiwan
Uruguay
Turkey
Australia
Singapore
Latvia
Colombia

EPA-registered manufacturers (1)

Companies that report making or importing this chemical to the EPA. Registration is US-centric and does not indicate import origin.

Hexion

Why It Matters

Sectors

HealthConstruction

Downstream Uses

Appears in 1 drug and cosmetic product listings (FDA).

•MILKBODyLotion

FDA Shortage Status

Whether any manufacturer currently reports this drug as in shortage on the FDA Drug Shortages database. "Active Shortage" means at least one presentation has status "current."

No FDA shortage records

Industrial Uses

•Intermediate in Wood Product Manufacturing (100%)Processing as a reactant

Vendor Pricing

$256.00/gA2B Chem LLC

CountryUnited States

Pack$256.00 / 1 g

Purity95%

Vendors3 available

Prices reflect listed pack sizes. Small research packs run far above bulk rates.

2 more vendors

Vendor	Country	$/g	Pack	Purity
AA BLOCKS	United States	$266.00	1 g	95%
Angene International Limited	United States	$464.00	1 g	95%

Chemical Identity

CAS1000-82-4

PubChem CID13842

DTXSIDDTXSID5027350

FormulaC2H6N2O2

Mol. Weight90.08 g/mol

SMILESC(NC(=O)N)O

Data Sources

EPA CompTox (DSSTox) · DTXSID5027350Retrieved 2026-04-06
PubChem · compound 13842Retrieved 2026-04-06
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
EPA Chemical Data ReportingReporting year: 2023 · Retrieved 2026-10-04
US Census international tradeReporting year: 2024 · Retrieved 2026-10-04

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Brief citations

1-(Hydroxymethyl)urea (CAS 1000-82-4) https://chemicalindependence.com/chemical/1000-82-4/ EPA CompTox (DSSTox): DTXSID5027350. Retrieved 2026-04-06. https://comptox.epa.gov/dashboard/chemical/details/DTXSID5027350 PubChem: 13842. Retrieved 2026-04-06. https://pubchem.ncbi.nlm.nih.gov/compound/13842 EPA Chemical Data Reporting: 1000-82-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting EPA Chemical Data Reporting: CAS 1000-82-4. Reporting year: 2023. https://www.epa.gov/chemical-data-reporting US Census international trade: HS 292419 for CAS 1000-82-4. Reporting year: 2024. https://usatrade.census.gov/